🧬 Receptor activity
| Target | Action | Affinity | Source | |
|---|---|---|---|---|
| Prostaglandin G/H synthase 1 (PTGS1) | Inhibitor | 5.16 IC50 | DRUGCENTRAL | TargetProstaglandin G/H synthase 1 (PTGS1) ActionInhibitor Affinity5.16 IC50 SourceDRUGCENTRAL |
| Prostaglandin G/H synthase 2 (PTGS2) | Inhibitor | 5.6 IC50 | DRUGCENTRAL | TargetProstaglandin G/H synthase 2 (PTGS2) ActionInhibitor Affinity5.6 IC50 SourceDRUGCENTRAL |
| Aldo-keto reductase family 1 member C2 (AKR1C2) | — | 4.5 IC50 | DRUGCENTRAL | TargetAldo-keto reductase family 1 member C2 (AKR1C2) Action— Affinity4.5 IC50 SourceDRUGCENTRAL |
| Aldo-keto reductase family 1 member C3 (AKR1C3) | — | 6.32 IC50 | DRUGCENTRAL | TargetAldo-keto reductase family 1 member C3 (AKR1C3) Action— Affinity6.32 IC50 SourceDRUGCENTRAL |
| Cyclooxygenase (Ptgs2) | — | 7.22 IC50 | DRUGCENTRAL | TargetCyclooxygenase (Ptgs2) Action— Affinity7.22 IC50 SourceDRUGCENTRAL |
| Hormone-sensitive lipase (Lipe) | — | 5.92 IC50 | DRUGCENTRAL | TargetHormone-sensitive lipase (Lipe) Action— Affinity5.92 IC50 SourceDRUGCENTRAL |
| Prostaglandin G/H synthase 1 (PTGS1) | — | 6.74 IC50 | DRUGCENTRAL | TargetProstaglandin G/H synthase 1 (PTGS1) Action— Affinity6.74 IC50 SourceDRUGCENTRAL |
| Prostaglandin G/H synthase 2 (PTGS2) | — | 5.47 IC50 | DRUGCENTRAL | TargetProstaglandin G/H synthase 2 (PTGS2) Action— Affinity5.47 IC50 SourceDRUGCENTRAL |
| Prostaglandin-H2 D-isomerase (Ptgds) | — | 4.89 IC50 | DRUGCENTRAL | TargetProstaglandin-H2 D-isomerase (Ptgds) Action— Affinity4.89 IC50 SourceDRUGCENTRAL |
External links
PubChem 156391 ↗CAS 22204-53-1 ↗KEGG C01517 ↗ChEBI CHEBI:7476 ↗ChEMBL CHEMBL154 ↗KEGG D00118 ↗DrugBank DB00788 ↗NIH ↗NIH ↗NIH ↗NIH ↗ChemSpider ↗ChEBI/ChEMBL ↗ChEBI/ChEMBL ↗Guide to Pharmacology ↗NIH ↗NIH ↗NIH ↗NIH ↗DrugBank ↗ChEBI/ChEMBL ↗NIH ↗NIH ↗NIH ↗NIH ↗NIH ↗NIH ↗NIH ↗NIH ↗NIH ↗NIH ↗NIH ↗CAS 131991-52-1 ↗CAS 23979-41-1 ↗CAS 26159-31-9 ↗CAS 51091-84-0 ↗PsychonautWiki ↗Erowid ↗Experience reports (PiHKAL) ↗Experience reports (TiHKAL) ↗
Source: DrugCentral — Naproxen ↗
Fact-sheets from PsychonautWiki. Harm-reduction reference only — not medical advice.