Pentobarbital
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4 sources
🧬 Receptor activity
| Target | Action | Affinity | Source | |
|---|---|---|---|---|
| GABA-A receptor alpha-1/beta-2/gamma-2 (GABRA1) | Positive allosteric modulator | 4.301 EC50 | DRUGCENTRAL | TargetGABA-A receptor alpha-1/beta-2/gamma-2 (GABRA1) ActionPositive allosteric modulator Affinity4.301 EC50 SourceDRUGCENTRAL |
| Gamma-aminobutyric acid receptor subunit beta-3 (GABRB3) | Positive allosteric modulator | 4.06 IC50 | DRUGCENTRAL | TargetGamma-aminobutyric acid receptor subunit beta-3 (GABRB3) ActionPositive allosteric modulator Affinity4.06 IC50 SourceDRUGCENTRAL |
| GABA A receptor alpha-2/beta-2/gamma-2 (GABRG2) | — | 4.3 EC50 | DRUGCENTRAL | TargetGABA A receptor alpha-2/beta-2/gamma-2 (GABRG2) Action— Affinity4.3 EC50 SourceDRUGCENTRAL |
| GABA-A receptor; anion channel (Gabrp) | — | 5.77 IC50 | DRUGCENTRAL | TargetGABA-A receptor; anion channel (Gabrp) Action— Affinity5.77 IC50 SourceDRUGCENTRAL |
| Potassium voltage-gated channel subfamily H member 2 (KCNH2) | — | 2.553 IC50 | DRUGCENTRAL | TargetPotassium voltage-gated channel subfamily H member 2 (KCNH2) Action— Affinity2.553 IC50 SourceDRUGCENTRAL |
External links
PubChem 4737 ↗CAS 76-74-4 ↗KEGG C07422 ↗ChEBI CHEBI:7983 ↗ChEMBL CHEMBL448 ↗KEGG D00499 ↗DrugBank DB00312 ↗NIH ↗NIH ↗NIH ↗ChemSpider ↗ChEBI/ChEMBL ↗Guide to Pharmacology ↗NIH ↗NIH ↗NIH ↗NIH ↗DrugBank ↗ChEBI/ChEMBL ↗CAS 30849-50-4 ↗CAS 57-33-0 ↗CAS 5767-32-8 ↗PsychonautWiki ↗Erowid ↗Experience reports (PiHKAL) ↗Experience reports (TiHKAL) ↗
Source: DrugCentral — Pentobarbital ↗
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