Pethidine
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Also known as Pethidine, Meperidine, Demerol, Dolantin, Dolcontral
Fatal overdose may occur when opiates are combined with other depressants such as benzodiazepines, barbiturates, gabapentinoids, thienodiazepines, alcohol or other GABAergic substances.[1] It is strongly discouraged to combine these substances, particularly in common to heavy doses.
Addiction potential
extremely addictive with a high potential for abuse
Toxicity
high toxicity; potentially lethal when mixed with depressants like alcohol or benzodiazepines
Tolerance
full tolerance develops with prolonged and repeated use; half after 3 - 7 days; baseline after 1 - 2 weeks
Cross-tolerance
opioids
Oral
Route dataPsychonautWiki
| Threshold | Light | Common | Strong | Heavy |
|---|---|---|---|---|
| 25 mg | 50–100 mg | 100–200 mg | 200–400 mg | —+ |
0400 mg
LightCommonStrongHeavy
| Onset | 30–60 minutes |
|---|---|
| Peak | 4–6 hours |
| After-effects | 2–10 hours |
OnsetCome-upPeakOffset
Dangerous interactions
Caution / uncertain
Plan when to take Pethidine — see where onset, peak and comedown land on the clock
Plan a dose of Pethidine
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Source: PsychonautWiki — Pethidine ↗
Fact-sheets from PsychonautWiki. Harm-reduction reference only — not medical advice.