Phenazepam
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Collated from TripSit, Pharmacology. Where sources differ (e.g. dosing), Compare shows them side by side.
A very long acting, potent and subtle benzodiazepine. Infamous for the calamitous experiences it tends to produce in people dosing unknown amounts. Prescribed in certain countries for epilepsy and alcohol withdrawal.TS
Oral
Route dataTripSit
| Threshold | Light | Common | Strong | Heavy |
|---|---|---|---|---|
| — | 0.5–1 mg | 1–2 mg | — | 2 mg+ |
02.5 mg
LightCommonStrongHeavy
| Onset | 15–60 minutes |
|---|---|
| Total | 18 hours |
| After-effects | 36 hours |
OnsetCome-upPeakOffset
🧬 Receptor activityPH
| Target | Action | Affinity | Source | |
|---|---|---|---|---|
| GABA-A receptor; alpha-1/beta-2/gamma-2 | — | Ki 0.05 nM | CHEMBL | TargetGABA-A receptor; alpha-1/beta-2/gamma-2 Action— AffinityKi 0.05 nM SourceCHEMBL |
| GABA A receptor alpha-2/beta-2/gamma-2 | — | Ki 0.06 nM | CHEMBL | TargetGABA A receptor alpha-2/beta-2/gamma-2 Action— AffinityKi 0.06 nM SourceCHEMBL |
| GABA A receptor alpha-3/beta-2/gamma-2 | — | Ki 0.12 nM | CHEMBL | TargetGABA A receptor alpha-3/beta-2/gamma-2 Action— AffinityKi 0.12 nM SourceCHEMBL |
| Gamma-aminobutyric acid receptor subunit alpha-5/beta-2/gamma-2 | — | Ki 0.68 nM | CHEMBL | TargetGamma-aminobutyric acid receptor subunit alpha-5/beta-2/gamma-2 Action— AffinityKi 0.68 nM SourceCHEMBL |
Plan when to take Phenazepam — see where onset, peak and comedown land on the clock
Plan a dose of Phenazepam
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