← hubDrugs

Phenobarbital

Discover related

4 sources

← All substances
🔗 MergedComparePsychonautWikiTripSitPharmacologyDrugCentral

How the databases line up — = agree, partial, differ. In lists, shared items appear in every source and unique ones in only one (matched case-insensitively).

Show:
PsychonautWikiTripSitPharmacologyDrugCentral
Classification
Class / category
Also known as
PhenobarbitalPhenobarbitoneLuminalPhenobarb
phenophenobarbitoneluminal
Safety
Addiction potentialextremely physically and psychologically addictive
Toxicity
moderate toxicitypotentially lethal when mixed with depressants like alcohol or opioids
Dose · Oral
Threshold25 mg
Light50–100 mg50–100 mg=
Common100–150 mg100–150 mg=
Strong150–300 mg150–300 mg=
Duration
Onset15–60 minutes
Total4–6 hours
After-effects1–48 hours1–24 hours
Pharmacology
Receptor activity
GABRA1NR1I2NR1I3Scn1a
Half-life53 to 118 hours (mean 79 hours) The plasma half-life for phenobarbital in adults ranges between 53 and 118 hours with an mean of 79 hours. The plasma half-life for phenobarbital in children and newborns (less than 48 hours old) ranges between 60 to 180 hours with a mean of 110 hours.
Protein binding20 to 45%

Dose at a glance

Each database's primary-route ladder on one shared scale — see where ranges line up or shift.

PsychonautWiki oral
TripSit Oral
0300 mg
LightCommonStrongHeavy

PsychonautWiki summary

Death may occur when barbiturates are combined with depressants such as opiates, benzodiazepines, gabapentinoids, thienodiazepines, alcohol or other GABAergic substances.[1] It is strongly discouraged to consume moderate to heavy dosages of these substances together.

TripSit summary

CNS depressant that is used mostly for insomnia (In older patients) and epliepsy (in younger patients) And it a very strong narcotic, that can be taken most ways. It's used less as "safer" alternatives have been made (Benzodiazepines).

Fact-sheets from PsychonautWiki. Harm-reduction reference only — not medical advice.