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Phenobarbital

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Also known as Phenobarbital, Phenobarbitone, Luminal, Phenobarb

Death may occur when barbiturates are combined with depressants such as opiates, benzodiazepines, gabapentinoids, thienodiazepines, alcohol or other GABAergic substances.[1] It is strongly discouraged to consume moderate to heavy dosages of these substances together.

Addiction potential
extremely physically and psychologically addictive
Toxicity
moderate toxicity; potentially lethal when mixed with depressants like alcohol or opioids

Oral

Route dataPsychonautWiki

ThresholdLightCommonStrongHeavy
25 mg50–100 mg100–150 mg150–300 mg—+
0300 mg
LightCommonStrongHeavy
Onset15–60 minutes
Come-up1–2 hours
Peak4–6 hours
Offset12–24 hours
Total4–6 hours
After-effects1–48 hours
OnsetCome-upPeakOffset
Plan when to take Phenobarbital — see where onset, peak and comedown land on the clock

Source: PsychonautWiki — Phenobarbital ↗

Fact-sheets from PsychonautWiki. Harm-reduction reference only — not medical advice.