How the databases line up — = agree, ≈ partial, ≠ differ. In lists, shared items appear in every source and unique ones in only one (matched case-insensitively).
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| TripSit | Pharmacology | DrugCentral | DailyMed | ||
|---|---|---|---|---|---|
| Classification | |||||
| Class / category | — | — | — | ||
| Also known as | inderalhemangeolinnopran | — | — | — | |
| Safety | |||||
| Dose · Oral | |||||
| Light | 10–30 mg | — | — | — | |
| Common | 40–80 mg | — | — | — | |
| Strong | 80–140 mg | — | — | — | |
| Duration | |||||
| Onset | 10–45 minutes | — | — | — | |
| Total | 3–7 hours | — | — | — | |
| After-effects | 1–8 hours | — | — | — | |
| Pharmacology | |||||
| Receptor activity | — | Beta-2 adrenergic receptorSigma non-opioid intracellular receptor 1Sigma intracellular receptor 25-hydroxytryptamine receptor 65-hydroxytryptamine receptor 1A5-hydroxytryptamine receptor 2C5-hydroxytryptamine receptor 2AAlpha-1B adrenergic receptor | ADRB1ADRB2ADRB3HTR1AHTR1BHTR1DHTR2AHTR2BHTR2CHTR6CYP1A2CYP2D6Drd2HRH1Pgrmc1ABCB1HCN4SIGMAR1SLC6A4SLC22A1CACNA1C | — | ≠ |
| Half-life | — | The elimination half-life of propranolol is approximately 8 hours. The plasma half-life of propranolol is 3 to 6 hours. | — | — | |
| Protein binding | — | Approximately 90% of propranolol is protein bound in plasma. Other studies have reported ranges of 85-96%. | — | Approximately 90% of circulating propranolol is bound to plasma proteins (albumin and alpha1 acid glycoprotein). The binding is enantiomer-selective. The S(-)-enantiomer is preferentially bound to alpha1 glycoprotein and the R(+)-enantiomer preferentially bound to albumin. The volume of distribution of propranolol is approximately 4 liters/kg. Propranolol crosses the blood-brain barrier and the placenta, and is distributed into breast milk. | ≠ |
TripSit summary
Is a nonselective beta blocker. It is used in medication for high blood pressure, anxiety, and tremors. Also fun fact, it was the first successful beta-blocker developed.
Fact-sheets from PsychonautWiki. Harm-reduction reference only — not medical advice.