Psilocin

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Class

Psychedelic Substituted tryptamines Tentative Empathogen Research-chemical

Dose

Weaker Stronger

Duration

Shorter Longer

3 sources

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🔗 Merged Compare PsychonautWiki TripSit Pharmacology

🧬 Receptor activity

Target	Action	Affinity	Source
5-hydroxytryptamine receptor 2B	—	Ki 4.6 nM	CHEMBL
5-hydroxytryptamine receptor 1D	—	Ki 19 nM	CHEMBL
D(1A) dopamine receptor	—	Ki 20 nM	CHEMBL
5-hydroxytryptamine receptor 2A	—	Ki 25 nM	CHEMBL
5-hydroxytryptamine receptor 1E	—	Ki 44 nM	CHEMBL
5-hydroxytryptamine receptor 1A	—	Ki 63 nM	CHEMBL
5-hydroxytryptamine receptor 5A	—	Ki 70 nM	CHEMBL
5-hydroxytryptamine receptor 6	—	Ki 72 nM	CHEMBL
5-hydroxytryptamine receptor 7	—	Ki 72 nM	CHEMBL
D(3) dopamine receptor	—	Ki 100 nM	CHEMBL
5-hydroxytryptamine receptor 2C	—	Ki 140 nM	CHEMBL
5-hydroxytryptamine receptor 1B	—	Ki 305 nM	CHEMBL
Adenosine receptor A2b	—	Ki 1300 nM	CHEMBL
Adenosine receptor A2a	—	Ki 2000 nM	CHEMBL
D(1B) dopamine receptor	—	Ki 10000 nM	CHEMBL
D(2) dopamine receptor	—	Ki 10000 nM	CHEMBL
Adenosine receptor A1	—	Ki 10000 nM	CHEMBL
D(4) dopamine receptor	—	Ki 10000 nM	CHEMBL
Unchecked	—	Ki 10000 nM	CHEMBL

Pharmacokinetics

Metabolism

Psilocin has known human metabolites that include (2S,3S,4S,5R)-6-[[3-[2-(dimethylamino)ethyl]-1H-indol-4-yl]oxy]-3,4,5-trihydroxyoxane-2-carboxylic acid.

Fact-sheets from PsychonautWiki. Harm-reduction reference only — not medical advice.

Psilocin

🧬 Receptor activity

Pharmacokinetics

Metabolism

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