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Also known as S-Adenosyl Methionine, SAM-e, Methylguanidoacetic Acid

Addiction potential
not habit-forming with a low potential for abuse

Oral

Route dataPsychonautWiki

ThresholdLightCommonStrongHeavy
200 mg400–800 mg800–1200 mg1200–1600 mg1600 mg+
02000 mg
LightCommonStrongHeavy
Onset100–180 minutes
OnsetCome-upPeakOffset

Source: PsychonautWiki — SAM-e ↗

Fact-sheets from PsychonautWiki. Harm-reduction reference only — not medical advice.