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Sertraline

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🔗 MergedCompareTripSitPharmacologyDrugCentralDailyMed

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TripSitPharmacologyDrugCentralDailyMed
Classification
Class / category
Also known as
zoloftlustral
Safety
Duration
Pharmacology
Receptor activity
SERTSodium-dependent serotonin transporterSodium-dependent dopamine transporterSigma non-opioid intracellular receptor 1Alpha-2B adrenergic receptorAlpha-2A adrenergic receptorNorepinephrine transporterMuscarinic acetylcholine receptor M1Alpha-1B adrenergic receptorMuscarinic acetylcholine receptor M5Muscarinic acetylcholine receptor M45-hydroxytryptamine receptor 2CAlpha-2C adrenergic receptor5-hydroxytryptamine receptor 2ASodium-dependent noradrenaline transporterMuscarinic acetylcholine receptor M2Unchecked5-hydroxytryptamine receptor 2BMelanocortin receptor 5Sigma intracellular receptor 2Voltage-gated inwardly rectifying potassium channel KCNH2
SLC6A4HTR2AHTR2BHTR2CADRA1AAdra1bADRA2AADRA2BADRA2CCYP2C19MC5RPgrmc1CHRM1CHRM2CHRM3CHRM4CHRM5KCNH2SIGMAR1SLC6A3SLC6A2luxR
Half-lifeThe elimination half-life of sertraline is approximately 26 hours. One reference mentions an elimination half-life ranging from 22-36 hours. Elimination half-life, parent (metabolite): 24 (65) hours. /from table/ Elimination half-life: 24 to 26 hours
Protein bindingSertraline is highly bound to serum proteins, at about 98%-99%.

Fact-sheets from PsychonautWiki. Harm-reduction reference only — not medical advice.