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| TripSit | Pharmacology | ||
|---|---|---|---|
| Classification | |||
| Safety | |||
| Dose · Oral | |||
| Light | 100–200 mg | — | |
| Common | 200–300 mg | — | |
| Strong | 300–600 mg | — | |
| Heavy | 600 mg+ | — | |
| Duration | |||
| Onset | 2–3 hours | — | |
| Total | 30–40 hours | — | |
| Pharmacology | |||
| Receptor activity | — | Phosphodiesterase 4Adenosine receptor A3Adenosine receptor A1Adenosine receptor A2aAdenosine A2 receptor | |
| Half-life | — | The mean half-time of theobromine in human serum ranged from 6.1 to 10 hr. The disposition half-life of theobromine averaged 7.1 +/- 2.1 hours ... In dogs, an average plasma half-time of 17.5 hr was reported after single oral doses of theobromine ranging from 15 to 150 mg/kg bw. In rabbits, the mean elimination half-time was 4.3-5.6 hr for doses ranging from 1 to 100 mg/kg bw. | |
TripSit summary
Theobromine is the principal bitter alkaloid of the cacao bean. It has been used in various pharmaceutical products as vasodilator, diuretic and as heart stimulant. Theobromine is consumed in cocoa, chocolate and in various forms of chocolate-based foods. It is also present in small amounts in green coffee beans, tea, mate and the kola nut.
Fact-sheets from PsychonautWiki. Harm-reduction reference only — not medical advice.