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Also known as U-47700

Fatal overdose may occur when opiates are combined with other depressants such as benzodiazepines, barbiturates, gabapentinoids, thienodiazepines, alcohol or other GABAergic substances.[1] It is strongly discouraged to combine these substances, particularly in common to heavy doses.

Addiction potential
moderately addictive with a high potential for abuse
Toxicity
high toxicity relative to its dose due to its extreme potency; potentially lethal when mixed with depressants like alcohol or benzodiazepines
Tolerance
full tolerance develops with prolonged and repeated use; half after 3 - 7 days; baseline after 1 - 2 weeks
Cross-tolerance
opioids

Insufflated

Route dataPsychonautWiki

ThresholdLightCommonStrongHeavy
1 mg4–6 mg6–8 mg8–10 mg10 mg+
012.5 mg
LightCommonStrongHeavy
Onset5–10 minutes
Come-up15–20 minutes
Peak1–2 hours
Total2–3 hours
After-effects2–4 hours
OnsetCome-upPeakOffset

Caution / uncertain

Plan when to take U-47700 — see where onset, peak and comedown land on the clock

Source: PsychonautWiki — U-47700 ↗

Fact-sheets from PsychonautWiki. Harm-reduction reference only — not medical advice.