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4-AcO-DET

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3 sources

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🔗 MergedComparePsychonautWikiTripSitPharmacology

Collated from PsychonautWiki, TripSit, Pharmacology. Where sources differ (e.g. dosing), Compare shows them side by side.

Sections
PsychedelicSubstituted tryptaminesTentativeResearch-chemicalPW

Also known as 4-AcO-DET, 4-Acetoxy-DET, Ethacetin, ethylacybinPW

Rare drug that is of the tryptamine family, can be comparable to Psilocybin. Expected to quickly hydrolyzed into the free phenolic 4-HO-DET.TS

Addiction potentialPW
not habit-forming
ToxicityPW
toxic dose is unknown
TolerancePW
full tolerance almost immediately after ingestion; half after 3 days; baseline after 7 days
Cross-tolerancePW
psychedelic

Oral

Route dataPsychonautWiki

Dose
WeakerStronger
ThresholdLightCommonStrongHeavy
5 mg10–15 mg15–20 mg20–35 mg35 mg+
043.75 mg
LightCommonStrongHeavy
Duration
ShorterLonger
Onset20–60 minutes
Come-up1–1.5 hours
Peak1.5–3 hours
Offset1–2 hours
Total4–7 hours
After-effects2–4 hours
OnsetCome-upPeakOffset

Dangerous interactionsPW

Lithium

Unsafe interactionsPW

Tramadol

Caution / uncertainPW

CannabisStimulants

🧬 Receptor activityPH

TargetActionAffinitySource
Sodium/potassium-transporting ATPase subunit alpha-2/beta-3—Ki 14.4 nMCHEMBL
Sodium/potassium-transporting ATPase subunit alpha-2/beta-2—Ki 16.4 nMCHEMBL
Sodium/potassium-transporting ATPase subunit alpha-2/beta-1—Ki 23.2 nMCHEMBL
Sodium/potassium-transporting ATPase subunit alpha-1/beta-1—Ki 138 nMCHEMBL
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Plan when to take 4-AcO-DET — see where onset, peak and comedown land on the clock

Fact-sheets from PsychonautWiki. Harm-reduction reference only — not medical advice.