Alprazolam
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5 sources
🧬 Receptor activity
| Target | Action | Affinity | Source | |
|---|---|---|---|---|
| GABA-A receptor alpha-1/beta-2/gamma-2 (GABRA1) | Positive allosteric modulator | 7.432 EC50 | DRUGCENTRAL | TargetGABA-A receptor alpha-1/beta-2/gamma-2 (GABRA1) ActionPositive allosteric modulator Affinity7.432 EC50 SourceDRUGCENTRAL |
| GABA-A receptor alpha-2/beta-3/gamma-2 (GABRG2) | Positive allosteric modulator | 7.921 EC50 | DRUGCENTRAL | TargetGABA-A receptor alpha-2/beta-3/gamma-2 (GABRG2) ActionPositive allosteric modulator Affinity7.921 EC50 SourceDRUGCENTRAL |
| GABA-A receptor alpha-3/beta-3/gamma-2 (GABRG2) | Positive allosteric modulator | 7.161 EC50 | DRUGCENTRAL | TargetGABA-A receptor alpha-3/beta-3/gamma-2 (GABRG2) ActionPositive allosteric modulator Affinity7.161 EC50 SourceDRUGCENTRAL |
| GABA-A receptor alpha-5/beta-3/gamma-2 (GABRG2) | Positive allosteric modulator | 8 EC50 | DRUGCENTRAL | TargetGABA-A receptor alpha-5/beta-3/gamma-2 (GABRG2) ActionPositive allosteric modulator Affinity8 EC50 SourceDRUGCENTRAL |
| Bromodomain-containing protein 4 (BRD4) | — | 5.61 Kd | DRUGCENTRAL | TargetBromodomain-containing protein 4 (BRD4) Action— Affinity5.61 Kd SourceDRUGCENTRAL |
| Cholecystokinin receptor type A (Cckar) | — | 4.19 IC50 | DRUGCENTRAL | TargetCholecystokinin receptor type A (Cckar) Action— Affinity4.19 IC50 SourceDRUGCENTRAL |
| Cytochrome P450 3A4 (CYP3A4) | — | 3.85 Ki | DRUGCENTRAL | TargetCytochrome P450 3A4 (CYP3A4) Action— Affinity3.85 Ki SourceDRUGCENTRAL |
| Platelet-activating factor receptor (PTAFR) | — | 5.457 Ki | DRUGCENTRAL | TargetPlatelet-activating factor receptor (PTAFR) Action— Affinity5.457 Ki SourceDRUGCENTRAL |
External links
PubChem 2118 ↗CAS 28981-97-7 ↗KEGG C06817 ↗ChEBI CHEBI:2611 ↗ChEMBL CHEMBL661 ↗KEGG D00225 ↗DrugBank DB00404 ↗NIH ↗ChemSpider ↗ChEBI/ChEMBL ↗ChEBI/ChEMBL ↗Guide to Pharmacology ↗NIH ↗NIH ↗NIH ↗NIH ↗DrugBank ↗ChEBI/ChEMBL ↗NIH ↗NIH ↗CAS 112393-64-3 ↗CAS 1246182-61-5 ↗CAS 51339-48-1 ↗PsychonautWiki ↗Erowid ↗Experience reports (PiHKAL) ↗Experience reports (TiHKAL) ↗
Source: DrugCentral — Alprazolam ↗
Fact-sheets from PsychonautWiki. Harm-reduction reference only — not medical advice.