Baclofen
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4 sources
How the databases line up — = agree, ≈ partial, ≠ differ. In lists, shared items appear in every source and unique ones in only one (matched case-insensitively).
| PsychonautWiki | TripSit | Pharmacology | DrugCentral | ||
|---|---|---|---|---|---|
| Classification | |||||
| Class / category | — | — | ≈ | ||
| Also known as | BaclofenLioresal | gablofen | — | — | ≠ |
| Safety | |||||
| Addiction potential | moderately physically and psychologically addictive | — | — | — | |
| Toxicity | low toxicitypotentially lethal when mixed with depressants like alcohol, benzodiazepines or opioids | — | — | — | |
| Dangerous interactions | — | — | — | ||
| Dose · Oral | |||||
| Threshold | 5 mg | — | — | — | |
| Light | 10–20 mg | 10–20 mg | — | — | = |
| Common | 20–50 mg | 20–50 mg | — | — | = |
| Strong | 50–100 mg | 50–75 mg | — | — | ≠ |
| Heavy | 100 mg+ | 75 mg+ | — | — | ≠ |
| Duration | |||||
| Onset | 30–75 minutes | 15–45 minutes | — | — | ≠ |
| Total | 8–14 hours | 3–6 hours | — | — | ≠ |
| After-effects | 6–12 hours | 1–6 hours | — | — | ≠ |
| Pharmacology | |||||
| Receptor activity | — | — | UncheckedGABA-B receptor | GABBR2ADORA3Gabrp | ≠ |
| Half-life | — | — | The half-life is 2-6 hours after oral administration and 1-5 hours following intrathecal administration. The apparent elimination half-life of baclofen oral suspension or granules is about 5.6 hours. | — | |
| Protein binding | — | — | The protein binding is approximately 30%. | — | |
Dose at a glance
Each database's primary-route ladder on one shared scale — see where ranges line up or shift.
Duration at a glance
Total duration on one shared scale.
PsychonautWiki summary
This page has not been fully approved by the PsychonautWiki administrators. It may contain incorrect information, particularly with respect to dosage, duration, subjective effects, toxicity and other risks. It may also not meet PW style and grammar standards.
TripSit summary
Also known as Lioresal, Baclofen is a GABAb receptor agonist and central nervous system depressant used to treat spasticity, and holds promise as a treatment for alcoholism. It exhibits mild intoxicating effects similar to phenibut or pregabalin.
Fact-sheets from PsychonautWiki. Harm-reduction reference only — not medical advice.