Baclofen
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4 sources
Also known as Baclofen, Lioresal
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Addiction potential
moderately physically and psychologically addictive
Toxicity
low toxicity; potentially lethal when mixed with depressants like alcohol, benzodiazepines or opioids
Tolerance
full tolerance within a couple of days of continuous use; baseline after 7 - 14 days
Cross-tolerance
GABA
Oral
Route dataPsychonautWiki
| Threshold | Light | Common | Strong | Heavy |
|---|---|---|---|---|
| 5 mg | 10–20 mg | 20–50 mg | 50–100 mg | 100 mg+ |
0125 mg
LightCommonStrongHeavy
| Onset | 30–75 minutes |
|---|---|
| Come-up | 1–1.5 hours |
| Peak | 1–2 hours |
| Offset | 1.5–2.5 hours |
| Total | 8–14 hours |
| After-effects | 6–12 hours |
OnsetCome-upPeakOffset
Dangerous interactions
Plan when to take Baclofen — see where onset, peak and comedown land on the clock
Plan a dose of Baclofen
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Logging a dose needs somewhere to keep it. Start a free session — no signup; it and everything in it expire in 7 days.
Source: PsychonautWiki — Baclofen ↗
Fact-sheets from PsychonautWiki. Harm-reduction reference only — not medical advice.