Diazepam
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Also known as Valium, Diastat, Mother's Little Helper, Apaurin
Fatal overdose may occur when benzodiazepines are combined with other depressants such as opiates, barbiturates, gabapentinoids, thienodiazepines, alcohol or other GABAergic substances.[1] It is strongly discouraged to combine these substances, particularly in common to heavy doses.
Addiction potential
extremely physically and psychologically addictive
Toxicity
low toxicity; potentially lethal when mixed with depressants like alcohol or opioids
Tolerance
full tolerance within a couple of days of continuous use; baseline after 7-14 days
Cross-tolerance
benzodiazepines
Oral
Route dataPsychonautWiki
| Threshold | Light | Common | Strong | Heavy |
|---|---|---|---|---|
| 1 mg | 2.5–5 mg | 5–15 mg | 15–30 mg | 30 mg+ |
037.5 mg
LightCommonStrongHeavy
| Onset | 20–40 minutes |
|---|---|
| Peak | 60–90 minutes |
| Total | 4–8 hours |
| After-effects | 12–36 hours |
OnsetCome-upPeakOffset
Dangerous interactions
Plan when to take Diazepam — see where onset, peak and comedown land on the clock
Plan a dose of Diazepam
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Source: PsychonautWiki — Diazepam ↗
Fact-sheets from PsychonautWiki. Harm-reduction reference only — not medical advice.