Methamphetamine
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4 sources
🧬 Receptor activity
| Target | Action | Affinity | Source | |
|---|---|---|---|---|
| Sodium-dependent dopamine transporter (SLC6A3) | Inhibitor | 7.611 Ki | DRUGCENTRAL | TargetSodium-dependent dopamine transporter (SLC6A3) ActionInhibitor Affinity7.611 Ki SourceDRUGCENTRAL |
| Sodium-dependent noradrenaline transporter (SLC6A2) | Inhibitor | 7.91 Ki | DRUGCENTRAL | TargetSodium-dependent noradrenaline transporter (SLC6A2) ActionInhibitor Affinity7.91 Ki SourceDRUGCENTRAL |
| Sodium-dependent serotonin transporter (SLC6A4) | Inhibitor | 6.133 Ki | DRUGCENTRAL | TargetSodium-dependent serotonin transporter (SLC6A4) ActionInhibitor Affinity6.133 Ki SourceDRUGCENTRAL |
| Trace amine-associated receptor 1 (TAAR1) | Agonist | 5.89 EC50 | DRUGCENTRAL | TargetTrace amine-associated receptor 1 (TAAR1) ActionAgonist Affinity5.89 EC50 SourceDRUGCENTRAL |
| 5-hydroxytryptamine receptor 2B (HTR2B) | — | 5 Ki | DRUGCENTRAL | Target5-hydroxytryptamine receptor 2B (HTR2B) Action— Affinity5 Ki SourceDRUGCENTRAL |
| Alpha-2A adrenergic receptor (ADRA2A) | — | 5.383 Ki | DRUGCENTRAL | TargetAlpha-2A adrenergic receptor (ADRA2A) Action— Affinity5.383 Ki SourceDRUGCENTRAL |
| Alpha-2B adrenergic receptor (ADRA2B) | — | 6.128 Ki | DRUGCENTRAL | TargetAlpha-2B adrenergic receptor (ADRA2B) Action— Affinity6.128 Ki SourceDRUGCENTRAL |
| Alpha-2C adrenergic receptor (ADRA2C) | — | 6.09 Ki | DRUGCENTRAL | TargetAlpha-2C adrenergic receptor (ADRA2C) Action— Affinity6.09 Ki SourceDRUGCENTRAL |
| Sigma non-opioid intracellular receptor 1 (SIGMAR1) | — | 5.08 Ki | DRUGCENTRAL | TargetSigma non-opioid intracellular receptor 1 (SIGMAR1) Action— Affinity5.08 Ki SourceDRUGCENTRAL |
| Synaptic vesicular amine transporter (Slc18a2) | — | 5.61 Ki | DRUGCENTRAL | TargetSynaptic vesicular amine transporter (Slc18a2) Action— Affinity5.61 Ki SourceDRUGCENTRAL |
| Trace amine-associated receptor 1 (TAAR1) | — | 5.28 EC50 | DRUGCENTRAL | TargetTrace amine-associated receptor 1 (TAAR1) Action— Affinity5.28 EC50 SourceDRUGCENTRAL |
External links
PubChem 10836 ↗CAS 537-46-2 ↗KEGG C07164 ↗ChEBI CHEBI:6809 ↗ChEMBL CHEMBL1201201 ↗KEGG D08187 ↗DrugBank DB01577 ↗NIH ↗ChemSpider ↗ChEBI/ChEMBL ↗ChEBI/ChEMBL ↗NIH ↗NIH ↗DrugBank ↗ChEBI/ChEMBL ↗NIH ↗NIH ↗NIH ↗NIH ↗NIH ↗NIH ↗NIH ↗PsychonautWiki ↗Erowid ↗Experience reports (PiHKAL) ↗Experience reports (TiHKAL) ↗
Source: DrugCentral — Methamphetamine ↗
Fact-sheets from PsychonautWiki. Harm-reduction reference only — not medical advice.