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Also known as Methamphetamine, Meth, Crystal, Desoxyn, Speed, Ma, Ice, Glass, Shard, Tina, T, Tweak, Crank, Shabu, Yaba

Addiction potential
extremely addictive with a high potential for abuse
Tolerance
full tolerance rapidly develops with prolonged and repeated use; half after 3 - 7 days; baseline after 1 - 2 weeks
Cross-tolerance
dopamine, stimulants

Insufflated

Route dataPsychonautWiki

ThresholdLightCommonStrongHeavy
5 mg5–10 mg10–30 mg30–60 mg60 mg+
075 mg
LightCommonStrongHeavy
Onset3–5 minutes
Come-up3–5 minutes
Peak1.5–3 hours
Offset2–4 hours
Total4–7 hours
After-effects6–24 hours
OnsetCome-upPeakOffset

Intravenous

Route dataPsychonautWiki

ThresholdLightCommonStrongHeavy
5 mg5–10 mg10–30 mg30–40 mg40 mg+
050 mg
LightCommonStrongHeavy
Onset15–30 seconds
Come-up1–2 minutes
Peak1–3 hours
Offset3–4 hours
Total4–8 hours
After-effects12–24 Hours
OnsetCome-upPeakOffset

Oral

Route dataPsychonautWiki

ThresholdLightCommonStrongHeavy
5 mg5–10 mg10–25 mg25–50 mg50 mg+
062.5 mg
LightCommonStrongHeavy
Onset15–45 minutes
Come-up1–3 hours
Peak3–5 hours
Offset3–4 hours
Total8–12 hours
After-effects12–24 hours
OnsetCome-upPeakOffset

Rectal

Route dataPsychonautWiki

ThresholdLightCommonStrongHeavy
5 mg5–10 mg10–30 mg30–40 mg40 mg+
050 mg
LightCommonStrongHeavy
Onset5–15 minutes
Come-up3–5 minutes
Peak2–4 hours
Offset3–5 hours
Total6–10 hours
After-effects12–24 hours
OnsetCome-upPeakOffset

Smoked

Route dataPsychonautWiki

ThresholdLightCommonStrongHeavy
5 mg5–10 mg10–20 mg20–60 mg60 mg+
075 mg
LightCommonStrongHeavy
Onset7–10 seconds
Come-up5–10 seconds
Peak1–3 hours
Offset1–3 hours
Total2–6 hours
After-effects2–24 hours
OnsetCome-upPeakOffset

Dangerous interactions

Plan when to take Methamphetamine — see where onset, peak and comedown land on the clock

Source: PsychonautWiki — Methamphetamine ↗

Fact-sheets from PsychonautWiki. Harm-reduction reference only — not medical advice.