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An opioid analgesic drug with potency somewhere between tramadol and morphine, and with a similar action to Tramadol. Also an adrenergic reuptake inhibitor. High addiction potential. Potential for respiratory depression in overdose. Should not be combined with depressants or stimulants.

Oral

Route dataTripSit

ThresholdLightCommonStrongHeavy
25–50 mg50–75 mg75–150 mg—+
0150 mg
LightCommonStrongHeavy
After-effects1–12 hours

Source: TripSit — Tapentadol ↗

Fact-sheets from PsychonautWiki. Harm-reduction reference only — not medical advice.