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Also known as Tianeptine, Stablon, Coaxil, Tatinol

Addiction potential
mildly addictive
Toxicity
large therapeutic index and margin of safety
Tolerance
full tolerance with prolonged use; half after 3 - 7 days; baseline after 1 - 2 weeks
Cross-tolerance
trycyclic antidepressants, opioids

Oral

Route dataPsychonautWiki

ThresholdLightCommonStrongHeavy
3 mg6–12 mg12–35 mg35–100 mg100 mg+
0125 mg
LightCommonStrongHeavy
Onset30–60 minutes
Come-up15–30 minutes
Peak60–90 minutes
Offset30–60 minutes
Total2–3 hours
OnsetCome-upPeakOffset
Plan when to take Tianeptine — see where onset, peak and comedown land on the clock

Source: PsychonautWiki — Tianeptine ↗

Fact-sheets from PsychonautWiki. Harm-reduction reference only — not medical advice.