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A Tricyclic antidepressant, that has quite unique pharmacological properties than others in its class. Such as the possible indirect action on NMDA/AMPA and a full agonist at the μ-opioid receptor. While abuse of this substance is uncommon, it has been shown in a few countries.

Oral

Route dataTripSit

Onset15–45 minutes
Total4–6 hours
After-effects1–8 hours
OnsetCome-upPeakOffset
Plan when to take Tianeptine — see where onset, peak and comedown land on the clock

Source: TripSit — Tianeptine ↗

Fact-sheets from PsychonautWiki. Harm-reduction reference only — not medical advice.