Diphenhydramine
Discover related
4 sources
Also known as DPH, Benadryl, Nytol, Sominex, Unisom SleepMelts, ZzzQuil
Diphenhydramine use is associated with highly uncomfortable and/or dangerous experiences. Deliriants are highly unpredictable and may result in erratic behaviors, self-injury, hospitalization, or death. It should be noted that most individuals do not choose to repeat the experience due to its unpleasant nature.
Addiction potential
produces dependence with chronic use
Toxicity
fatal at amounts close to or exceeding 2 grams
Tolerance
full tolerance with repeated use; baseline after 1 - 2 weeks
Cross-tolerance
deliriant
Oral
Route dataPsychonautWiki
| Threshold | Light | Common | Strong | Heavy |
|---|---|---|---|---|
| 25 mg | 100–200 mg | 200–400 mg | 400–700 mg | 700 mg+ |
0875 mg
LightCommonStrongHeavy
| Onset | 30–90 minutes |
|---|---|
| Come-up | 45–90 minutes |
| Peak | 1–4 hours |
| Offset | 2–6 hours |
| Total | 3–10 hours |
| After-effects | 24 hours |
OnsetCome-upPeakOffset
Plan when to take Diphenhydramine — see where onset, peak and comedown land on the clock
Plan a dose of Diphenhydramine
Loading the fact-sheet…
Logging a dose needs somewhere to keep it. Start a free session — no signup; it and everything in it expire in 7 days.
Fact-sheets from PsychonautWiki. Harm-reduction reference only — not medical advice.