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Diphenhydramine

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Also known as diphenhydramine, dph, benadryl

An antihistamine which, when taken in smaller doses relieves allergies and insomnia. In larger doses works as a deliriant and can actually keep the user awake. Generally the 'high' of this drug is reported as dysphoric, potentially causing hallucinations indistinguishable from reality.

Oral

Route dataTripSit

ThresholdLightCommonStrongHeavy
100–250 mg200–500 mg450–700 mg—+
0700 mg
LightCommonStrongHeavy
Onset60–120 minutes
Total6–8 hours
After-effects1–12 hours
OnsetCome-upPeakOffset

Dangerous interactions

Plan when to take Diphenhydramine — see where onset, peak and comedown land on the clock

Source: TripSit — Diphenhydramine ↗

Fact-sheets from PsychonautWiki. Harm-reduction reference only — not medical advice.