Methadone
Discover related
5 sources
🧬 Receptor activity
| Target | Action | Affinity | Source | |
|---|---|---|---|---|
| Mu-type opioid receptor (OPRM1) | Agonist | 8.78 Ki | DRUGCENTRAL | TargetMu-type opioid receptor (OPRM1) ActionAgonist Affinity8.78 Ki SourceDRUGCENTRAL |
| Delta-type opioid receptor (OPRD1) | — | 5.96 IC50 | DRUGCENTRAL | TargetDelta-type opioid receptor (OPRD1) Action— Affinity5.96 IC50 SourceDRUGCENTRAL |
| Glutamate receptor ionotropic, NMDA 3A (GRIN3A) | — | — | DRUGCENTRAL | TargetGlutamate receptor ionotropic, NMDA 3A (GRIN3A) Action— Affinity— SourceDRUGCENTRAL |
| Kappa-type opioid receptor (OPRK1) | — | 6.29 IC50 | DRUGCENTRAL | TargetKappa-type opioid receptor (OPRK1) Action— Affinity6.29 IC50 SourceDRUGCENTRAL |
| Neuronal acetylcholine receptor subunit alpha-10 (CHRNA10) | — | — | DRUGCENTRAL | TargetNeuronal acetylcholine receptor subunit alpha-10 (CHRNA10) Action— Affinity— SourceDRUGCENTRAL |
| Opioid receptor (Oprd1) | — | 7.29 IC50 | DRUGCENTRAL | TargetOpioid receptor (Oprd1) Action— Affinity7.29 IC50 SourceDRUGCENTRAL |
| Potassium voltage-gated channel subfamily H member 2 (KCNH2) | — | 5.01 IC50 | DRUGCENTRAL | TargetPotassium voltage-gated channel subfamily H member 2 (KCNH2) Action— Affinity5.01 IC50 SourceDRUGCENTRAL |
External links
PubChem 4095 ↗CAS 76-99-3 ↗KEGG C07163 ↗ChEBI CHEBI:167309 ↗ChEBI CHEBI:6807 ↗ChEMBL CHEMBL651 ↗KEGG D08195 ↗DrugBank DB00333 ↗NIH ↗NIH ↗ChemSpider ↗ChEBI/ChEMBL ↗ChEBI/ChEMBL ↗Guide to Pharmacology ↗NIH ↗NIH ↗DrugBank ↗ChEBI/ChEMBL ↗CAS 1095-90-5 ↗CAS 125-58-6 ↗CAS 297-88-1 ↗CAS 50630-93-8 ↗CAS 5653-80-5 ↗CAS 60263-63-0 ↗PsychonautWiki ↗Erowid ↗Experience reports (PiHKAL) ↗Experience reports (TiHKAL) ↗
Source: DrugCentral — Methadone ↗
Fact-sheets from PsychonautWiki. Harm-reduction reference only — not medical advice.