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A synthetic opioid drug used as an analgesic and is often used in detoxification off of other opioids. As it has a much longer half-life.

Oral

Route dataTripSit

ThresholdLightCommonStrongHeavy
5–10 mg10–20 mg20–35 mg—+
035 mg
LightCommonStrongHeavy
Onset45–120 minutes
After-effects1–48 hours
OnsetCome-upPeakOffset

Source: TripSit — Methadone ↗

Fact-sheets from PsychonautWiki. Harm-reduction reference only — not medical advice.